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Putting black pepper on your food may be one of the easiest, most economical ways to boost your overall wellbeing. Piperine, the main alkaloid from black pepper has been shown to substantially increase the bioavailability of the nutrients in foods and supplements. Piperine is a pungent compound found in the fruit of plants in the Piperaceae family, the most famous member of which is Piper nigrum, black pepper. Black pepper has a long history of use in Ayurvedic medicine as a restorative food. Piperine may help nutrients reach, enter and remain within their target cells for longer periods of time. As a result, a somewhat effective therapeutic substance may turn into a highly effective one by increasing its intracellular time.